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- Table of Contents
Facts about Probable small intestine urate exporter.
May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Willing to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro).
Human | |
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Gene Name: | SLC17A4 |
Uniprot: | Q9Y2C5 |
Entrez: | 10050 |
Belongs to: |
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major facilitator superfamily |
KAIA2138; KIAA2138; MGC129623; Na/PO4 cotransporter; putative small intestine sodium-dependent phosphate transport protein; solute carrier family 17 (sodium phosphate), member 4; Solute carrier family 17 member 4
Mass (kDA):
54.055 kDA
Human | |
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Location: | 6p22.2 |
Sequence: | 6; NC_000006.12 (25754673..25781199) |
Abundantly expressed in pancreas, liver, colon and small intestine, less in kidney. Not detected in the adrenal glands, brain, placenta, heart, testis, skeletal muscle, and lungs.
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Apical in the intestinal brush border.
PMID: 10319585 by Shibui A., et al. Isolation and chromosomal mapping of a novel human gene showing homology to Na+/PO4 cotransporter.
PMID: 22460716 by Togawa N., et al. A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter.