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- Table of Contents
Facts about Sodium-dependent phosphate transport protein 1.
Important for the resorption of phosphate by the kidney.
May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.Plays a role in urate transport in the kidney (PubMed:27906618). .
Human | |
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Gene Name: | SLC17A1 |
Uniprot: | Q14916 |
Entrez: | 6568 |
Belongs to: |
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major facilitator superfamily |
sodium-dependent phosphate transport protein 1; Na/Pi-4; NAPI-1; NPT1; NPT-1; SLC17A1; solute carrier family 17 (sodium phosphate), member 1
Mass (kDA):
51.132 kDA
Human | |
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Location: | 6p22.2 |
Sequence: | 6; NC_000006.12 (25723743..25832108, complement) |
Expressed in kidney cortex, liver and brain but not in other tissues.
Apical cell membrane; Multi-pass membrane protein.
PMID: 8288239 by Chong S.S., et al. Molecular cloning of the cDNA encoding a human renal sodium phosphate transport protein and its assignment to chromosome 6p21.3-p23.
PMID: 11704559 by Soumounou Y., et al. Murine and human type I Na-phosphate cotransporter genes: structure and promoter activity.