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- Table of Contents
Facts about Solute carrier family 12 member 7.
Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. Might be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity).
Human | |
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Gene Name: | SLC12A7 |
Uniprot: | Q9Y666 |
Entrez: | 10723 |
Belongs to: |
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SLC12A transporter family |
DKFZp434F076; KCC4; KCC4Electroneutral potassium-chloride cotransporter 4; K-Cl cotransporter 4; potassium/chloride transporter KCC4; SLC12A7; solute carrier family 12 (potassium/chloride transporters), member 7; solute carrier family 12 member 7
Mass (kDA):
119.106 kDA
Human | |
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Location: | 5p15.33 |
Sequence: | 5; NC_000005.10 (1050384..1155887, complement) |
Detected in muscle, brain, lung, heart and kidney.
Cell membrane; Multi-pass membrane protein.
PMID: 10347194 by Mount D.B., et al. Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family.
PMID: 11214971 by Hattori A., et al. Characterization of long cDNA clones from human adult spleen.