SLAM family member 6 Antibodies

AND Slamf6 ELISA kits, SLAM family member 6 Proteins

Many biological assays use antibodies to detect SLAM family member 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLAM family member 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLAM family member 6 antibodies...

We validate the specificity of these antibodies to SLAM family member 6 by testing them on tissues known to express Slamf6 positively and negatively. Browse below to find the Slamf6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Slamf6 Infographic by Boster Bio

All Slamf6 Products

Product

Figures

Specificity

Applications

Price

Anti-SLAF6 SLAMF6 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A05310
100ul

Human NTB-A/SLAMF6 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ96DU3
Starting from 10ug

Anti-SLAMF6 Antibody Picoband™

Human

ELISA, Flow Cytometry, WB

$370
Cat # A05310-2
100 µg/vial

Slamf6 Overview

Facts about SLAM family member 6.

SLAM family member 6 (Slamf6)

Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune reaction.

Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2 (PubMed:19648922). Triggers cytolytic action only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors (By similarity).

Gene Information

Mouse
Gene Name:	Slamf6
Uniprot:	Q9ET39
Entrez:	30925

Family

Belongs to:

No superfamily

Alternative Names

Activating NK receptor; CD352 antigen; CD352; KALIFLJ50657; Ly108; NK-T-B-antigen; NTBA receptor; NTBA; NTB-A; NTB-AMGC104953; NTBAT- and B-cell antigen; SF2000; SLAM family member 6; SLAMF6

Molecular Weight

Mass (kDA):
38.638 kDA

Genomic Context


Mouse

Location:	1 H3\|1 79.54 cM
Sequence:	1;

Tissue Specificity

Expressed on hematopoietic cells. Isoform 3 is expressed in thymocytes and B lymphocytes of C57Bl/6 strain.

Diseases

Lupus Erythematosus, Systemic
Tissue Adhesions
Immunologic Deficiency Syndromes
Malignant Neoplasms
Autoimmune Reaction
Neoplasms
Autoimmunity
Cell Transformation, Neoplastic
Radiation Chimera Disorder
Genetic Diseases, X-linked
Lung Diseases
Autoimmune Diseases

Diabetes Mellitus
Fibrosis
Severe Combined Immunodeficiency
Hiv Infections
Diabetes Mellitus, Insulin-dependent
Metaplastic Cell Transformation

Pathways

Cell Development
Cell Adhesion
Lymphocyte Activation
Germinal Center Formation
Cell Activation
Immune System Process
Multi-organism Process
T Cell Activation
Immune Response
Leukocyte Differentiation
Humoral Immune Response
Defense Response

Cell Maturation
System Process
Leukocyte Activation
Tolerance Induction
Cytokine Production
B Cell Adhesion
Cell Differentiation

PTMs

Disulfide bond

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slamf6

References

PMID: 11132158 by Peck S.R., et al. Ly108: a new member of the mouse CD2 family of cell surface proteins.

PMID: 21422172 by Keszei M., et al. A novel isoform of the Ly108 gene ameliorates murine lupus.