Spindle and kinetochore-associated protein 3 (Ska3)

Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct part of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies.

The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization.