SIGLEC9 Antibodies

AND SIGLEC9 ELISA kits, SIGLEC9 Proteins

Many biological assays use antibodies to detect SIGLEC9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SIGLEC9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SIGLEC9 antibodies...

We validate the specificity of these antibodies to SIGLEC9 by testing them on tissues known to express SIGLEC9 positively and negatively. Browse below to find the SIGLEC9 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SIGLEC9 Infographic by Boster Bio

All SIGLEC9 Products

Product

Figures

Specificity

Applications

Price

Anti-SIGLEC9 Antibody

Human, Mouse, Rat

$405
Cat # A06748
100ul

Human Siglec-9 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9Y336
Starting from 10ug

Anti-SIGLEC9 Mouse Monoclonal Antibody [Clone ID: OTI8F7]

Dog, Human, Monkey

IHC, WB

$523
Cat # M06748
100 µl

Anti-SIGLEC9 Mouse Monoclonal Antibody [Clone ID: OTI6D8]

Dog, Human, Monkey

IF, IHC, WB

$523
Cat # M06748-1
100 µl

SIGLEC9 (NM_014441) Human Over-expression Lysate

Human

$628
Cat # LS027180
100 µg

SIGLEC9 Overview

Facts about Sialic acid-binding Ig-like lectin 9.

SIGLEC9 3D structure. Source: alphafold

Sialic acid-binding Ig-like lectin 9 (SIGLEC9)

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid.

The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. .

Gene Information

Human
Gene Name:	SIGLEC9
Uniprot:	Q9Y336
Entrez:	27180

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

CD329; CDw329; FOAP-9; OBBP-Like; Protein FOAP-9; sialic acid binding Ig-like lectin 9; sialic acid-binding Ig-like lectin 9; Siglec9; Siglec-9

Molecular Weight

Mass (kDA):
50.082 kDA

Genomic Context


Human

Location:	19q13.41
Sequence:	19; NC_000019.10 (51124880..51140480)

Tissue Specificity

Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils). Found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain, stomach, lung, thymus, prostate, brain, mammary, adrenal gland, colon, trachea, cerebellum, testis, small intestine and spinal cordon.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Neoplasms
Autoimmune Reaction
Inflammation
Malignant Neoplasms
Septic Shock
Basophilic Leukemia
Chimera Disorder
Ovarian Neoplasm
Tissue Adhesions
Autoimmune Diseases
Leukemia
Neoplasm Metastasis

Colonic Neoplasms
Pre-eclampsia
Pseudomonas Infections
Carcinogenesis
Carcinoma
Leukemia, Myelocytic, Acute
Myeloid Leukemia

Interacting Proteins

TLR4

Pathways

Cell Death
Pathogenesis
Immune Response
Cell Adhesion
Cell Activation
Programmed Cell Death
Glycosylation
Endocytosis
Localization
Leukocyte Migration

Mrna Splicing
Cytokine Production
Phagocytosis
Innate Immune Response
Secretion

PTMs

Phosphorylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SIGLEC9

References

PMID: 10903842 by Foussias G., et al. Identification and molecular characterization of a novel member of the siglec family (SIGLEC9).

PMID: 10801862 by Zhang J.Q., et al. Siglec-9, a novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes.