SH3TC2 Antibodies

AND SH3TC2 ELISA kits, SH3TC2 Proteins

Many biological assays use antibodies to detect SH3TC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SH3TC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SH3TC2 antibodies...

We validate the specificity of these antibodies to SH3TC2 by testing them on tissues known to express SH3TC2 positively and negatively. Browse below to find the SH3TC2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SH3TC2 Infographic by Boster Bio

All SH3TC2 Products

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Anti-SH3TC2 Antibody

Human

ELISA, IHC

$380
Cat # A06580
100ul

SH3TC2 Overview

Facts about SH3 domain and tetratricopeptide repeat-containing protein 2.

SH3TC2 3D structure. Source: alphafold

SH3 domain and tetratricopeptide repeat-containing protein 2 (SH3TC2)

Gene Information

Human
Gene Name:	SH3TC2
Uniprot:	Q8TF17
Entrez:	79628

Family

Belongs to:

No superfamily

Alternative Names

SH3 domain and tetratricopeptide repeats 2

Molecular Weight

Mass (kDA):
144.777 kDA

Genomic Context


Human

Location:	5q32
Sequence:	5; NC_000005.10 (148982150..149063062, complement)

Tissue Specificity

Strongly expressed in brain and spinal cord. Expressed at equal level in spinal cord and sciatic nerve. Weakly expressed in striated muscle.

Diseases

Charcot-marie-tooth Disease
Charcot-marie-tooth Disease, Type 4c
Scoliosis, Unspecified
Hereditary Motor And Sensory Neuropathies
Peripheral Neuropathy
Sensory Neuropathy
Nervousness
Inherited Neuropathy
Foot Deformities
Polyneuropathy
Congenital Abnormality

Charcot-marie-tooth Disease, Type 4a (disorder)
Weakness
Dejerine-sottas Disease (disorder)
Tissue Adhesions
Demyelination
Congenital Foot Deformity

Pathways

Mitochondrial Fusion
Endocytic Recycling
Pathogenesis
Localization
Myelination
Transport
Cell Adhesion

Endosome Localization
Single Strand Break Repair

PTMs

Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SH3TC2

References

PMID: 14574644 by Senderek J., et al. Mutations in a gene encoding a novel SH3/TPR domain protein cause autosomal recessive Charcot-Marie-Tooth type 4C neuropathy.

PMID: 20220177 by Lupski J.R., et al. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy.