SH3RF1 Antibodies

AND SH3RF1 ELISA kits, SH3RF1 Proteins

Many biological assays use antibodies to detect SH3RF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SH3RF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SH3RF1 antibodies...

We validate the specificity of these antibodies to SH3RF1 by testing them on tissues known to express SH3RF1 positively and negatively. Browse below to find the SH3RF1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: LRRN1

SH3RF1 Infographic by Boster Bio

All SH3RF1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

SH3MD2 (SH3RF1) (NM_020870) Human Recombinant Protein

$1249
Cat # PROTQ7Z6J0
20 µg

SH3MD2 (SH3RF1) (NM_020870) Human Over-expression Lysate

Human

$960
Cat # LS057630
100 µg

SH3RF1 Overview

Facts about E3 ubiquitin-protein ligase SH3RF1.

SH3RF1 3D structure. Source: alphafold

E3 ubiquitin-protein ligase SH3RF1 (SH3RF1)

Acts as a scaffold protein, results in Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity).

May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. .

Gene Information

Human
Gene Name:	SH3RF1
Uniprot:	Q7Z6J0
Entrez:	57630

Family

Belongs to:

SH3RF family

Alternative Names

EC 6.3.2; EC 6.3.2.-; KIAA1494SH3 multiple domains protein 2; Plenty of SH3s; POSHFLJ21602; Protein POSH; putative E3 ubiquitin-protein ligase SH3RF1; RING finger protein 142; RNF142plenty of SH3 domains; SH3 domain containing ring finger 1; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3MD2

Molecular Weight

Mass (kDA):
93.129 kDA

Genomic Context


Human

Location:	4q32.3-q33
Sequence:	4; NC_000004.12 (169094259..169270956, complement)

Subcellular Localizations

Cytoplasm, perinuclear region. Cell projection, lamellipodium. Golgi apparatus, trans-Golgi network. Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network.