SH2D4A Antibodies

AND SH2D4A ELISA kits, SH2D4A Proteins

Many biological assays use antibodies to detect SH2D4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SH2D4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SH2D4A antibodies...

We validate the specificity of these antibodies to SH2D4A by testing them on tissues known to express SH2D4A positively and negatively. Browse below to find the SH2D4A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SH2D4A Infographic by Boster Bio

All SH2D4A Products

Product

Figures

Specificity

Applications

Price

Anti-SH2D4A Antibody

Human, Mouse, Rat

$405
Cat # A09094
100ul

Anti-SH2D4A Antibody

Human

ELISA, IHC

$380
Cat # A09094-1
100ul

Anti-SH2D4A Antibody Picoband™

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A09094-2
100 μg/vial

SH2D4A Overview

Facts about SH2 domain-containing protein 4A.

SH2D4A 3D structure. Source: alphafold

SH2 domain-containing protein 4A (SH2D4A)

Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.

Gene Information

Human
Gene Name:	SH2D4A
Uniprot:	Q9H788
Entrez:	63898

Family

Belongs to:

No superfamily

Alternative Names

Protein SH(2)A; SH2 domain containing 4A; SH2 domain-containing protein 4A; SH2AFLJ20967

Molecular Weight

Mass (kDA):
52.727 kDA

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (19313570..19396218)

Tissue Specificity

Ubiquitously expressed. Aberrantly expressed in some cancers.

Subcellular Localizations

Cytoplasm. Located at podocyte foot processes.

Diseases

Malignant Neoplasms
Neoplasms
Liver Carcinoma
Hepatitis
Malignant Neoplasm Of Breast
Hepatitis B
Hypokinesia
Carcinoma
Virus Diseases

Listeriosis
Loss Of Chromosome 8p
Liver Neoplasms
Simian B Disease

Pathways

Cell Proliferation
Cell Development
Cell Growth
Intracellular Signal Transduction
Mating
Pathogenesis

Localization

PTMs

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SH2D4A

References

PMID: 12476414 by Dai S., et al. A novel member of SH(2) signaling protein family: cloning and characterization of SH(2)A gene.

PMID: 18641339 by Lapinski P.E., et al. Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells.