Gamma-sarcoglycan Antibodies

AND SGCG ELISA kits, Gamma-sarcoglycan Proteins

Many biological assays use antibodies to detect Gamma-sarcoglycan, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gamma-sarcoglycan in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gamma-sarcoglycan antibodies...

We validate the specificity of these antibodies to Gamma-sarcoglycan by testing them on tissues known to express SGCG positively and negatively. Browse below to find the SGCG antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SGCG Infographic by Boster Bio

All SGCG Products

Product

Figures

Specificity

Applications

Price

Anti-gamma Sarcoglycan Rabbit Monoclonal Antibody

7 Q&As

Human

IP, IHC, WB

$370
Cat # M05934
100 μl

Anti-Sarcoglycan Gamma SGCG Antibody

Human, Mouse

IP, IHC, WB

$405
Cat # A05934
100ul

SGCG Overview

Facts about Gamma-sarcoglycan.

SGCG 3D structure. Source: alphafold

Gamma-sarcoglycan (SGCG)

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. .

Gene Information

Human
Gene Name:	SGCG
Uniprot:	Q13326
Entrez:	6445

Family

Belongs to:

sarcoglycan beta/delta/gamma/zeta family

Alternative Names

35 kDa dystrophin-associated glycoprotein; 35DAG; A4; DAGA4,35kD dystrophin-associated glycoprotein; DMDA; DMDA1; gamma sarcoglycan; gamma-sarcoglycan; gamma-SG; MAM; MGC130048; sarcoglycan, gamma (35kD dystrophin-associated glycoprotein); sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein); SCARMD2; SCG3LGMD2C; TYPE

Molecular Weight

Mass (kDA):
32.379 kDA

Genomic Context


Human

Location:	13q12.12
Sequence:	13; NC_000013.11 (23160508..23325162)

Tissue Specificity

Expressed in skeletal and heart muscle.

Subcellular Localizations

Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.

Diseases

Muscular Dystrophy
Muscular Dystrophies, Limb-girdle
Dystrophy
Sarcoglycanopathies
Severe Autosomal Recessive Muscular Dystrophy Of Childhood - North African Type (disorder)
Fibrosis
Congenital Muscular Dystrophy (disorder)
Muscular Dystrophy, Duchenne
Hereditary Diseases
Inflammation
Myelinated Retinal Nerve Fibers

Ataxia
Neuromuscular Diseases
Myopathy
Trembling
Congenital Anomaly Of Brain
Spastic Ataxia, Charlevoix-saguenay Type

Interacting Proteins

ACO1
DNAJB6
DYSF

Pathways

Dna Repair
Chromosome Segregation

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SGCG

References

PMID: 7481775 by Noguchi S., et al. Mutations in the dystrophin-associated protein gamma-sarcoglycan in chromosome 13 muscular dystrophy.

PMID: 8900232 by McNally E.M., et al. Mild and severe muscular dystrophy caused by a single gamma- sarcoglycan mutation.