Sftpa1 Antibodies

Pulmonary surfactant-associated protein A (Sftpa1)

In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (PubMed:25965346).

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Gene Information

Mouse
Gene Name:	Sftpa1
Uniprot:	P35242
Entrez:	20387

Family

Belongs to:
SFTPA family

Alternative Names

COLEC4; PSAP; PSPA; PSP-A; SFTP1; SFTPA1; SFTPA1B; SPA; SP-A; SPA1; SP-A1; surfactant protein A1B

Molecular Weight

Mass (kDA):
26.157 kDA

Genomic Context

Mouse
Location:	14 B|14 22.36 cM
Sequence:	14;

Diseases

• Respiratory Distress
• Respiratory Distress Syndrome, Newborn
• Adenocarcinoma
• Lung Diseases
• Fibrosis
• Inflammation
• Lung Neoplasms
• Adenocarcinoma Of Lung (disorder)
• Pneumonia
• Dysequilibrium Syndrome
• Cystic Fibrosis

• Neoplasms
• Pulmonary Alveolar Proteinosis
• Pulmonary Fibrosis
• Premature Birth
• Meningococcal Infections
• Malignant Neoplasms

Pathways

• Phagocytosis
• Translation
• Secretion
• Glycosylation
• Pathogenesis
• Parturition
• Lung Development
• Inflammatory Response
• Immune Response
• Proteolysis
• Regulation Of Gene Expression
• Localization

• Cytokine Production
• Reverse Transcription
• Mrna Transcription
• Cell Death
• Interphase
• Lung Morphogenesis

PTMs

• Glycosylation
• Phosphorylation

• Cleavage
• Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sftpa1

Best Uses Of The SFTPA1 Marker From Boster Bio

This article will discuss the many benefits of the SFTPA1 marker by Boster Bio. Apart from the advantages of the marker, this guide will be able to answer some concerns you may have. Troubleshooting guides will help you determine the source of the error and the best way to eliminate it. For more information, please look up SFTA1_HUMAN_Q8IWL2A. It is a purified recombinant protein.

Boster's SFTPA1 marker has many advantages

Clinical trials show that SFTPA1 variants are becoming well-known as diagnostic markers. This is due to the fact that SFTPA1 is a possible marker for lung cancer and other malignancies. Studies conducted by Zhang et al. Zhang and Zhang. have discovered a C-to–A transversion in exon 6 of the SFTPA1 genes, which results in a gln238–to-lys substitution. Of the 30 patients that were studied three were homozygous for the variant as were eight out of 30 healthy volunteers. The difference between patients and the controls was significant, indicating that the mutation could alter the 3D structure of the protein.

Troubleshooting guide

When using the SFTPA1 marker troubleshooting is a vital element of the diagnostic procedure. The enzyme-linked immunosorbent assay (ELISA) requires several elements and steps. Oftentimes, a single error could lead to an unintended outcome. Below are some typical issues and their solutions. This guide will help you solve these problems. It will help you determine if you have a specific genetic mutation.

SFTA1_HUMAN-Q8IWL2A

The SFTPA1 marker, a homologous Homo sapiens protein is used. It was isolated using affinity columns for anti-DDK as well as conventional chromatography techniques. Boster Bio provides comprehensive technical assistance for optimizing experiments and reproducing results. Troubleshooting guides can help you identify the source of error. These guides can also be used to reduce the amount of cross-linking.

Purified recombinant protein

Boster Bio purified recombinants are derived from the human ubiquitin-associated proteins (UAP1) gene. This protein was derived by using affinity columns that are anti-DDK and conventional chromatography procedures. The company offers credit for product for sharing the results. It also offers customized services and beNeLux delivery. Here's a quick overview of the purification process.

The company was founded in 1993 by renowned histologist Steven Xia, Boster Bio focuses on manufacturing high-specificity antibodies with high-sensitivity. In the last two decades, Boster Bio has refined their methods and techniques to create high-quality recombinant antibody. More than 29,000 scientific publications have referenced their products. In addition, they offer a quality guarantee. They also back their products.