SERTAD1 Antibodies

AND SERTAD1 ELISA kits, SERTAD1 Proteins

Many biological assays use antibodies to detect SERTAD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SERTAD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SERTAD1 antibodies...

We validate the specificity of these antibodies to SERTAD1 by testing them on tissues known to express SERTAD1 positively and negatively. Browse below to find the SERTAD1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SERTAD1 Infographic by Boster Bio

All SERTAD1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SERTAD1 Antibody

1 Citations

Human, Mouse, Rat

$405
Cat # A09983
100ul

Human SERTAD1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9UHV2
Starting from 4ug

SERTAD1 (NM_013376) Human Over-expression Lysate

Human

$628
Cat # LS029950
100 µg

SERTAD1 Overview

Facts about SERTA domain-containing protein 1.

SERTAD1 3D structure. Source: alphafold

SERTA domain-containing protein 1 (SERTAD1)

Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity.

Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A. .

Gene Information

Human
Gene Name:	SERTAD1
Uniprot:	Q9UHV2
Entrez:	29950

Family

Belongs to:

No superfamily

Alternative Names

SEI-1; SEI1CDK4-binding protein p34SEI1; SERTA domain containing 1; SERTA domain-containing protein 1; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP-Br1CDK4-binding protein p34SEI

Molecular Weight

Mass (kDA):
24.704 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (40421589..40425992, complement)

Diseases

Malignant Neoplasms
Neoplasms
Mammary Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Carcinoma
Malignant Tumor Of Cervix
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Genomic Instability
Retinoblastoma
Carcinoma, Transitional Cell

Melanoma
Colonic Neoplasms
Dermatitis, Atopic
Neoplasms, Experimental
Malignant Tumor Of Colon
Malignant Neoplasm Of Urinary Bladder
Head And Neck Neoplasms

Interacting Proteins

KLHL42
SETD7

Pathways

Cell Cycle
Cell Growth
Cell Death
Regulation Of Cell Cycle
Cell Proliferation
Cell Cycle Arrest
Senescence
Secretion
Programmed Cell Death
Insulin Secretion
Glucocorticoid Secretion
Proteolysis
Neuron Death

Cortisol Secretion
Nuclear Division
Dna Replication
Response To Ionizing Radiation
S Phase
Response To Reactive Oxygen Species
Histone Acetylation

PTMs

Phosphorylation
Ubiquitination

Cleavage
Acetylation

Dephosphorylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERTAD1

References

PMID: 10580009 by Sugimoto M., et al. Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI- 1).

PMID: 11331592 by Hsu S.-I., et al. TRIP-Br: a novel family of PHD zinc finger- and bromodomain- interacting proteins that regulate the transcriptional activity of E2F-1/DP-1.

1 Publications of Boster SERTAD1 Antibodies & ELISA Kits

PubMed ID: 10.1111/j.1440-1681.2009.05181.x, CONTINUOUS FLUOXETINE ADMINISTRATION PREVENTS RECURRENCE OF PULMONARY ARTERIAL H...

*More publications can be found for each product on its corresponding product page