Plasma protease C1 inhibitor (SERPING1)

Activation of the C1 complex is under control of the C1- inhibitor.

It creates a proteolytically inactive stoichiometric complex with the C1r or C1s proteases.

May play a potentially crucial role in regulating significant physiological pathways such as complement activation, blood coagulation, fibrinolysis and the creation of kinins. Very efficient inhibitor of FXIIa.