C1QA Antibodies

AND C1QA ELISA kits, C1QA Proteins

Many biological assays use antibodies to detect C1QA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C1QA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C1QA antibodies...

We validate the specificity of these antibodies to C1QA by testing them on tissues known to express C1QA positively and negatively. Browse below to find the C1QA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C1QA Infographic by Boster Bio

All C1QA Products

Product

Figures

Specificity

Applications

Price

Anti-C1QA Antibody

Human

ELISA, WB

$380
Cat # A01955
100ul

C1QA (NM_015991) Human Over-expression Lysate

Human

$628
Cat # LS000712
100 µg

Anti-C1QA Rabbit Monoclonal Antibody

Human, Rat

IHC, WB

$370
Cat # M01955
100 µl/vial

C1QA Overview

Facts about Complement C1q subcomponent subunit A.

C1QA 3D structure. Source: alphafold

Complement C1q subcomponent subunit A (C1QA)

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like areas of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 occurs on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Gene Information

Human
Gene Name:	C1QA
Uniprot:	P02745
Entrez:	712

Family

Belongs to:

No superfamily

Alternative Names

C1QA complement component 1, q subcomponent, A chain; C1QA; Complement Component C1qA

Molecular Weight

Mass (kDA):
26.017 kDA

Genomic Context


Human

Location:	1p36.12
Sequence:	1; NC_000001.11 (22636628..22639682)

Subcellular Localizations

Secreted.

Diseases

Lupus Erythematosus, Systemic
Autoimmune Reaction
Autoimmune Diseases
Glomerulonephritis
Autoimmunity
Malignant Neoplasms
Neoplasms
Nephritis
Inflammation
Neurodegenerative Disorders
Neoplasm Metastasis
Lupus Nephritis
Mammary Neoplasms

Communicable Diseases
Nervousness
Atherosclerosis
Peripheral Nerve Injuries
Polyneuropathy
Malignant Neoplasm Of Breast
Leishmaniasis, Visceral

Interacting Proteins

C1QB
C1QBP
UBQLN2

Pathways

Complement Activation
Pathogenesis
Immune Response
Aging
Regeneration
Apoptotic Cell Clearance
Cell Activation
Respiratory Burst
Histone Modification
Localization
Inflammatory Response
Fatty Acid Homeostasis

Tissue Regeneration
Phagocytosis
Regulation Of Complement Activation
Cell Differentiation
Angiogenesis
Secretion

PTMs

Phosphorylation

Cleavage

Research Areas

Immunology
Innate Immunity

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C1QA

References

PMID: 1706597 by Sellar G.C., et al. Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q.

PMID: 486087 by Reid K.B.M.; Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement.