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SERPINF1 Antibodies
AND SERPINF1 ELISA kits, SERPINF1 Proteins
Many biological assays use antibodies to detect SERPINF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SERPINF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SERPINF1 antibodies...
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SERPINF1 Infographic by Boster Bio
All SERPINF1 Products
Product
Figures
Specificity
Applications
Price
Human PEDF/SerpinF1 ELISA Kit PicoKine®
2 Citations 17 Q&As
Human
ELISA
$499
Cat # EK0896
96 wells/kit, with removable strips.
Cat # EK0896
96 wells/kit, with removable strips.
SERPINF1 Overview
Facts about Pigment epithelium-derived factor.
Pigment epithelium-derived factor (SERPINF1)
Neurotrophic proteininduces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis.
As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SERPINF1 |
| Uniprot: | P36955 |
| Entrez: | 5176 |
Family
| Belongs to: |
|---|
| serpin family |
Alternative Names
Cell proliferation-inducing gene 35 protein; EPC-1; EPC-1PIG35; PEDF; PEDFpigment epithelium-derived factor; pigment epithelium derived factor), member 1; proliferation-inducing protein 35; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin; Serpin F1; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epitheliumderived factor), member 1
Molecular Weight
Mass (kDA):
46.312 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.3 |
| Sequence: | 17; NC_000017.11 (1761925..1777574) |
Tissue Specificity
Retinal pigment epithelial cells and blood plasma.
Subcellular Localizations
Secreted. Melanosome. Enriched in stage I melanosomes.
Diseases
- Malignant Neoplasms
- Osteogenesis Imperfecta
- Neoplasms
- Tumor Angiogenesis
- Obesity
- Carcinoma
- Diabetes Mellitus
- Fracture
- Tissue Adhesions
- Cell Transformation, Neoplastic
- Hereditary Diseases
- Congenital Abnormality
- Diabetes Mellitus, Non-insulin-dependent
Interacting Proteins
- EPM2AIP1
Pathways
- Angiogenesis
- Cell Adhesion
- Secretion
- Transport
- Cell Proliferation
- Pathogenesis
- Tube Formation
- Endothelial Cell Proliferation
- Nuclear Transport
- Cell Division
- Chemotaxis
- System Development
- Cell Cycle
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINF1
bosterbio.com/bosterbio-gene-info-cards/SERPINF1
References
PMID: 8434014 by Steele F.R., et al. Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family.
PMID: 9238088 by Tombran-Tink J., et al. Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin.
4 Publications of Boster SERPINF1 Antibodies & ELISA Kits
- PubMed ID: 10.1159/000497612, Pigment Epithelium-Derived Factor Affects Angiogenesis in Celiac Disease
- PubMed ID: 22495066, Polyethylene glycol-modified pigment epithelial-derived factor: new prospects fo...
- PubMed ID: 21139695, Administration of pigment epithelium-derived factor delivered by adeno-associate...
- PubMed ID: 27936049, Clinicopathological Features and Prognosis of Papillary Thyroid Microcarcinoma f...
*More publications can be found for each product on its corresponding product page