Serpin B10 Antibodies

AND SERPINB10 ELISA kits, Serpin B10 Proteins

Many biological assays use antibodies to detect Serpin B10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Serpin B10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Serpin B10 antibodies...

We validate the specificity of these antibodies to Serpin B10 by testing them on tissues known to express SERPINB10 positively and negatively. Browse below to find the SERPINB10 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SERPINB10 Infographic by Boster Bio

All SERPINB10 Products

Product

Figures

Specificity

Applications

Price

Anti-SPB10 SERPINB10 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A11520
100ul

SERPINB10 (NM_005024) Human Recombinant Protein

$1249
Cat # PROTP48595
20 µg

SERPINB10 (NM_005024) Human Over-expression Lysate

Human

$628
Cat # LS005273
100 µg

SERPINB10 Overview

Facts about Serpin B10.

SERPINB10 3D structure. Source: alphafold

Serpin B10 (SERPINB10)

Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.

Gene Information

Human
Gene Name:	SERPINB10
Uniprot:	P48595
Entrez:	5273

Family

Belongs to:

serpin family

Alternative Names

bomapin; Peptidase inhibitor 10; PI-10; PI10protease inhibitor 10 (ovalbumin type, bomapin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10; serpin B10; serpin peptidase inhibitor, clade B (ovalbumin), member 10

Molecular Weight

Mass (kDA):
45.403 kDA

Genomic Context


Human

Location:	18q22.1
Sequence:	18; NC_000018.10 (63907958..63936111)

Tissue Specificity

Expressed specifically in myeloid cells and the bone marrow.

Subcellular Localizations

Nucleus. Cytoplasm. Mostly found in the nucleus.

Diseases

Neoplasms
Leukemia
Myelomonocytic Leukemia
Leukemia, Myelocytic, Acute
Malignant Neoplasms
Myeloid Leukemia
Leukemia, Myelomonocytic, Chronic
Monosomy
Neoplasm Metastasis
Fracture Of First Cervical Vertebra
Complete Trisomy 18 Syndrome
Myeloid Leukemia, Chronic

Carcinogenesis
Acute Promyelocytic Leukemia
Monocytic Leukemia
Hematological Disease
Chronic Lymphocytic Leukemia
Dysequilibrium Syndrome
Turner Syndrome

Pathways

Translation
Cell Migration
Cell Proliferation
Dna Amplification
Coagulation
Cell Death
Fibrinolysis
Immune Response
Complement Activation

Autolysis
Localization
Secretion

PTMs

Disulfide bond

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINB10

References

PMID: 7592909 by Riewald M., et al. Molecular cloning of bomapin (protease inhibitor 10), a novel human serpin that is expressed specifically in the bone marrow.

PMID: 10196205 by Chuang T.L., et al. Identification of a nuclear targeting domain in the insertion between helices C and D in protease inhibitor-10.