Kallistatin Antibodies

Kallistatin (SERPINA4)

Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and creation of a tiny C-terminal fragment of the inhibitor due to cleavage in the reactive site by tissue kallikrein.

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Gene Information

Human
Gene Name:	SERPINA4
Uniprot:	P29622
Entrez:	5267

Family

Belongs to:
serpin family

Alternative Names

antitrypsin), member 4; KAL; Kallistatin; KLST; KSTKallikrein inhibitor; member 4; PI-4; PI4Peptidase inhibitor 4; protease inhibitor 4 (kallistatin); serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase; Serpin A4; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

Molecular Weight

Mass (kDA):
48.542 kDA

Genomic Context

Human
Location:	14q32.13
Sequence:	14; NC_000014.9 (94561442..94569906)

Tissue Specificity

Expressed by the liver and secreted in plasma.

Subcellular Localizations

Secreted.

Diseases

• Injury To Kidney
• Septic Shock
• Acute Kidney Injury

Pathways

• Pathogenesis

PTMs

• Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINA4

Best Uses Of The SERPINA4 Marker

Boster offers primary antibody products that are highly specific. They are also safe. These antibodies are applicable to all scientists from any part of the world. Boster will accept your results and issue product credits. Read on for more information. If you are interested in applying this marker to research, contact Boster today!

The research community has a trust in Boster's primary antibodies

Boster's high quality primary antibodies are highly regarded in the research community. These antibodies have been extensively validated on multiple matrices, including Western Blotting, Immunohistochemistry, and ELISA. Boster also offers detection kits. Since more than 25 year, the research community has trusted Boster because of its commitment to providing high quality products.

CiteAb data provides a quantitative overview of the research antibody marketplace based upon analysis of hundreds of thousand of antibody citations. CiteAb is the only company to provide data for all primary antibodies. It also provides detailed information on antibody reproducibility. Boster's quality program helps customers understand the scientific process behind their primary antibody. Boster's quality team is available 24/7 to help customers make the process simpler and more efficient.

Manipulating the antigen protein expression can produce a reliable primary antibody test. The same procedure can be used to prepare tissue from a knockout mouse. A nonfunctional gene prevents the expression or binding of the primary antibody to the tissue. Tissue from knockout animals can be used to control the expression of the antigen. It can also be used as an experimental sample.

Rockland not only provides reliable primary antibody, but also offers conjugated secondary antibodies for the detection and quantification of target proteins. These antibodies are suitable for immunoblotting, flow cytometry, immunohistochemistry, and ELISA. As a result, they are widely used in the research community. They can also be used in immunological techniques that require high specificity or titer.

The primary antibody should have colocalization with the fluorescent protein GFP. The two labels are located in the same spot, but not co-binding. The location of a single protein cannot be determined by light microscopes. Hence, antibodies should show co-localization. In fluorescent immunocytochemistry (FLUOR), the primary antibody must be co-localized with the GFP. This shows that the labels are in a single spot.

Boster's antibodies are specific

If you're interested in the SERPINA4 protein, you can purchase Boster Bio Anti-Kallistatin/SERPINA4 Antibody (catalog number PA1638). This antibody reacts well with human kallistatin. It contains 5 mg BSA. It is stable at -20C for one year and can be frozen for six months. It recognizes human Kallistatin (384-401aa AIKFFSAQTNRHILRFNR). To stop the antibody binding to the protein, you can buy a blocking propeptide.

Boster's antibodies can be used safely

Boster's antibodies are safe and simple to use. They have also been thoroughly tested for specificity and affinity. They are cited in many publications for their ability to repair DNA, maintain genomic stability, cause programmed cell deaths, and other research purposes. Besides the benefits of using Boster's antibodies, the safety of SERPINA4 markers in research has been validated by multiple methods, including PCR, Western blot, immunohistochemistry, and ELISA.