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- Table of Contents
Facts about Septin-7.
Involved in cytokinesis. Required for normal association of CENPE with the kinetochore.
Human | |
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Gene Name: | SEPTIN7 |
Uniprot: | Q16181 |
Entrez: | 989 |
Belongs to: |
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TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily |
Septin-7
Mass (kDA):
50.68 kDA
Human | |
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Location: | 7p14.2 |
Sequence: | 7; NC_000007.14 (35800986..35915763) |
Widely expressed.
Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase. Associated with actin stress fibers (By similarity). Found in the sperm annulus (PubMed:25588830).
PMID: 8037772 by Nakatsuru S., et al. Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae.
PMID: 15485874 by Nagata K., et al. Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.