Septin-6 Antibodies

AND SEPTIN6 ELISA kits, Septin-6 Proteins

Many biological assays use antibodies to detect Septin-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Septin-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Septin-6 antibodies...

We validate the specificity of these antibodies to Septin-6 by testing them on tissues known to express SEPTIN6 positively and negatively. Browse below to find the SEPTIN6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEPTIN6 Infographic by Boster Bio

All SEPTIN6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

SEPTIN6 (NM_145802) Human Recombinant Protein

$813
Cat # PROTQ14141
20 µg

SEPTIN6 (NM_145799) Human Over-expression Lysate

Human

$628
Cat # LS023157
100 µg

Anti-SEPT6/SEPTIN6 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A10957-4
100 μg/vial

SEPTIN6 Overview

Facts about Septin-6.

SEPTIN6 3D structure. Source: alphafold

Septin-6 (SEPTIN6)

Filament-forming cytoskeletal GTPase.
Required for normal organization of the actin cytoskeleton.

Involved in cytokinesis. May play a role in HCV RNA replication.

Gene Information

Human
Gene Name:	SEPTIN6
Uniprot:	Q14141
Entrez:	23157

Family

Belongs to:

TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily

Alternative Names

Septin-6

Molecular Weight

Mass (kDA):
49.717 kDA

Genomic Context


Human

Location:	Xq24
Sequence:	X; NC_000023.11 (119615724..119693196, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavage furrow. Midbody. Cell projection, cilium, flagellum. In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle. Found in the sperm annulus (PubMed:25588830).

Interacting Proteins

HNRNPA1
MORN4
PLEKHF2

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEPTIN6

References

PMID: 11809673 by Ono R., et al. SEPTIN6, a human homologue to mouse Septin6, is fused to MLL in infant acute myeloid leukemia with complex chromosomal abnormalities involving 11q23 and Xq24.

PMID: 15915442 by Hall P.A., et al. Expression profiling the human septin gene family.