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- Table of Contents
Facts about Selenide, water dikinase 1.
Human | |
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Gene Name: | SEPHS1 |
Uniprot: | P49903 |
Entrez: | 22929 |
Belongs to: |
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selenophosphate synthase 1 family |
EC 2.7.9.3; MGC4980; SELD; Selenium donor protein 1; Selenophosphate synthase 1; selenophosphate synthetase 1 +E9a; selenophosphate synthetase 1 delta E2; selenophosphate synthetase 1 delta E8; selenophosphate synthetase 1 major; selenophosphate synthetase 1; SPS1selenophosphate synthetase 1 +E9; water dikinase 1
Mass (kDA):
42.911 kDA
Human | |
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Location: | 10p13 |
Sequence: | 10; NC_000010.11 (13317428..13348298, complement) |
Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased. Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased.
[Isoform 1]: Cell membrane. Nucleus membrane.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.
PMID: 7665581 by Low S.C., et al. Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis.
PMID: 20471958 by Kim J.Y., et al. Human selenophosphate synthetase 1 has five splice variants with unique interactions, subcellular localizations and expression patterns.