Semaphorin-4A Antibodies

AND Sema4a ELISA kits, Semaphorin-4A Proteins

Many biological assays use antibodies to detect Semaphorin-4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Semaphorin-4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Semaphorin-4A antibodies...

We validate the specificity of these antibodies to Semaphorin-4A by testing them on tissues known to express Sema4a positively and negatively. Browse below to find the Sema4a antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: Sema4b

Sema4a Infographic by Boster Bio

All Sema4a Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SEMA4A/Semaphorin 4A Antibody

3 Q&As

Human, Monkey, Mouse, Rat

$399
Cat # A06779-1
100μl

Anti-SEMA4A (N532) Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A06779
100ul

SEMA4A (NM_022367) Human Recombinant Protein

$813
Cat # PROTQ9H3S1
20 µg

Anti-SEMA4A Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A06779-3
100 µg/vial

Sema4a Overview

Facts about Semaphorin-4A.

Semaphorin-4A (Sema4a)

Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an significant role in cell-cell signaling. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thus contributes to adaptive immunity.

Promotes phosphorylation of TIMD2. Inhibits angiogenesis.

Gene Information

Mouse
Gene Name:	Sema4a
Uniprot:	Q62178
Entrez:	20351

Family

Belongs to:

semaphorin family

Alternative Names

CORD10; RP35; Sema B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4A; SEMA4A; SEMAB; Semaphorin 4A; semaphorin-4A; semaphorin-B; SEMB; SEMBFLJ12287

Molecular Weight

Mass (kDA):
83.421 kDA

Genomic Context


Mouse

Location:	3\|3 F1
Sequence:	3;

Diseases

Nervousness
Retinal Degeneration
Autoimmune Reaction
Tumor Angiogenesis
Autoimmune Diseases
Retinitis Pigmentosa
Experimental Autoimmune Encephalomyelitis
Autoimmunity
Inflammation
Communicable Diseases
Asthma

Multiple Sclerosis
Encephalomyelitis
Sclerosis
Brain Ischemia
Fracture Of First Cervical Vertebra
Hypoxia

Pathways

Immune Response
Axon Guidance
Cell Activation
Angiogenesis
Cell Migration
T Cell Activation
Cell Death
Pathogenesis
Cell Adhesion
Response To Lipopolysaccharide
Circadian Rhythm
Signal Transmission
Localization

Macrophage Activation
Inflammatory Response
Response To Oxidative Stress
Regeneration
Endothelial Cell Migration
Phagocytosis
Cell Differentiation

PTMs

Disulfide bond

Glycoprotein

Research Areas

Neuroscience
Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sema4a

References

PMID: 7748561 by Pueschel A.W., et al. Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension.

PMID: 12374982 by Kumanogoh A., et al. Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.