SDR16C5 Antibodies

AND SDR16C5 ELISA kits, SDR16C5 Proteins

Many biological assays use antibodies to detect SDR16C5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SDR16C5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SDR16C5 antibodies...

We validate the specificity of these antibodies to SDR16C5 by testing them on tissues known to express SDR16C5 positively and negatively. Browse below to find the SDR16C5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SDR16C5 Infographic by Boster Bio

All SDR16C5 Products

Product

Figures

Specificity

Applications

Price

RDHE2 (SDR16C5) (NM_138969) Human Recombinant Protein

$1249
Cat # PROTQ8N3Y7
20 µg

RDHE2 (SDR16C5) (NM_138969) Human Over-expression Lysate

Human

$628
Cat # LS195814
100 µg

SDR16C5 Overview

Facts about Epidermal retinol dehydrogenase 2.

SDR16C5 3D structure. Source: alphafold

Epidermal retinol dehydrogenase 2 (SDR16C5)

Oxidoreductase with strong preference for NAD.
Active in both the oxidative and reductive directions.

Oxidizes all-trans- retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH.

Gene Information

Human
Gene Name:	SDR16C5
Uniprot:	Q8N3Y7
Entrez:	195814

Family

Belongs to:

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

EC 1.1.1.105; EPHD-2; epidermal retinol dehydrogenase 2; FLJ33105; RDH-E2epidermal retinal dehydrogenase 2; RDHE2RDH#2; retinal short chain dehydrogenase reductase; Retinal short-chain dehydrogenase reductase 2; retSDR2; short chain dehydrogenase/reductase family 16C, member 5; Short-chain dehydrogenase/reductase family 16C member 5

Molecular Weight

Mass (kDA):
34.095 kDA

Genomic Context


Human

Location:	8q12.1
Sequence:	8; NC_000008.11 (56299648..56320776, complement)

Tissue Specificity

Detected in adult lung. Detected at low levels in adult brain, heart, testis, placenta, cervix, pancreas, uterus, stomach, rectum, small intestine, colon, esophagus, thymus, skin, and skin keratinocyte. Expression is higher in psoriasis lesions relative to unaffected skin from psoriasis patients. Detected in fetal kidney, skin and lung.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Microcephaly

Pathways

Tube Closure
Neural Tube Closure
Somitogenesis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDR16C5

References

PMID: 12372410 by Matsuzaka Y., et al. Identification of the hRDH-E2 gene, a novel member of the SDR family, and its increased expression in psoriatic lesion.

PMID: 18926804 by Lee S.-A., et al. Biochemical characterization of human epidermal retinol dehydrogenase 2.