SDHC Antibodies

AND SDHC ELISA kits, SDHC Proteins

Many biological assays use antibodies to detect SDHC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SDHC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SDHC antibodies...

We validate the specificity of these antibodies to SDHC by testing them on tissues known to express SDHC positively and negatively. Browse below to find the SDHC antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SDHC Infographic by Boster Bio

All SDHC Products

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Product

Figures

Specificity

Applications

Price

Anti-SDHC Antibody Picoband®

5 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # PA1839
100 μg/vial

SDHC (NM_003001) Human Over-expression Lysate

Human

$628
Cat # LS006391
100 µg

Anti-SDHC Rabbit Monoclonal Antibody

Human, Mouse, Rat

IHC, WB

$370
Cat # M02725
100 µl/vial

SDHC Overview

Facts about Succinate dehydrogenase cytochrome b560 subunit, mitochondrial.

SDHC 3D structure. Source: alphafold

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC)

Membrane-anchoring subunit of succinate dehydrogenase (SDH) which is included in complex II of the mitochondrial electron transfer chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). .

Gene Information

Human
Gene Name:	SDHC
Uniprot:	Q99643
Entrez:	6391

Family

Belongs to:

cytochrome b560 family

Alternative Names

Integral membrane protein CII-3; mitochondrial; PGL3; QPs1; QPs-1; SDH3; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; succinate-ubiquinone oxidoreducatase cytochrome B large subunit

Molecular Weight

Mass (kDA):
18.61 kDA

Genomic Context


Human

Location:	1q23.3
Sequence:	1; NC_000001.11 (161314381..161375340)

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

Paraganglioma
Neoplasms
Pheochromocytoma
Von Hippel-lindau Syndrome
Adrenal Gland Neoplasms
Malignant Neoplasms
Head And Neck Neoplasms
Neurofibromatosis 1
Hereditary Paraganglioma
Malignant Paraganglionic Neoplasm
Cell Transformation, Neoplastic
Germline Mutation Abnormality
Neurofibromatoses

Multiple Endocrine Neoplasia
Endocrine Gland Neoplasms
Multiple Endocrine Neoplasia Type 2a
Carotid Body Paraganglioma
Extra-adrenal Paraganglioma
Hypoxia
Head And Neck Paraganglioma

Pathways

Transport
Electron Transport
Pathogenesis
Electron Transport Chain
Aging
Tricarboxylic Acid Cycle
Localization
Angiogenesis
Translation
Cell Proliferation
Oxidative Phosphorylation
Fermentation
Cell Growth

Excretion
Oxygen Homeostasis
Hypersensitivity
Sporulation
Cellular Respiration
Cell Cycle
Oncogenesis

PTMs

Reduction
Oxidation

Methylation
Phosphorylation

Cleavage

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDHC

References

PMID: 9533030 by Hirawake H., et al. Cytochrome b in human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the components in liver mitochondria and chromosome assignment of the genes for the large (SDHC) and small (SDHD) subunits to 1q21 and 11q23.

PMID: 9714607 by Elbehti-Green A., et al. Characterization of the human SDHC gene encoding one of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria.