SDHA Antibodies

AND SDHA ELISA kits, SDHA Proteins

Many biological assays use antibodies to detect SDHA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SDHA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SDHA antibodies...

We validate the specificity of these antibodies to SDHA by testing them on tissues known to express SDHA positively and negatively. Browse below to find the SDHA antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SDHA Infographic by Boster Bio

All SDHA Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SDHA Antibody Picoband®

5 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PB9433
100 μg/vial

Anti-SDHA Antibody Picoband®

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # PA1717
100 μg/vial

Anti-SDHA Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M01753
100 μl

Anti-SDHA Antibody Picoband®

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # A01753
100 μg/vial

Anti-SDHA Antibody

Human, Mouse, Rat, Zebrafish

Flow Cytometry, IF, IHC, ICC, WB

$405
Cat # A01753-1
100ul

SDHA (NM_004168) Human Over-expression Lysate

Human

$628
Cat # LS006389
100 µg

SDHA Overview

Facts about Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial.

SDHA 3D structure. Source: alphafold

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (SDHA)

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) which is included in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:24781757). Can function as a tumor suppressor (PubMed:20484225).

Gene Information

Human
Gene Name:	SDHA
Uniprot:	P31040
Entrez:	6389

Family

Belongs to:

FAD-dependent oxidoreductase 2 family

Alternative Names

CMD1GG; EC 1.3.5.1; Fp; SDH1; SDH2; SDHFmitochondrial; succinate dehydrogenase complex flavoprotein subunit; succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

Molecular Weight

Mass (kDA):
72.692 kDA

Genomic Context


Human

Location:	5p15.33
Sequence:	5; NC_000005.10 (218223..264816)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Diseases

Neoplasms
Paraganglioma
Pheochromocytoma
Malignant Neoplasms
Von Hippel-lindau Syndrome
Neurofibromatosis 1
Adrenal Gland Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Gastrointestinal Stromal Tumors
Malignant Paraganglionic Neoplasm
Hereditary Paraganglioma

Head And Neck Neoplasms
Neurofibromatoses
Hypoxia
Legionnaires' Disease
Endocrine Gland Neoplasms
Multiple Endocrine Neoplasia
Neoplasm Metastasis

Interacting Proteins

PTPN3
SDHAF2
SDHB

Pathways

Pathogenesis
Transport
Reverse Transcription
Electron Transport
Tricarboxylic Acid Cycle
Oxidative Phosphorylation
Cell Death
Electron Transport Chain
Localization
Virulence
Fermentation
Angiogenesis
Rna Interference

Embryo Development
Cell Proliferation
Dna Repair
Glycolysis
Immune Response
Translation
Mrna Transcription

PTMs

Phosphorylation
Oxidation
Cleavage
Methylation

Deacetylation
Acetylation
Carboxylation
Reduction

Research Areas

Hypoxia

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDHA

References

PMID: 7798181 by Hirawake H., et al. Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the flavoprotein (Fp) subunit of liver mitochondria.

PMID: 8142412 by Morris A.A.M., et al. The cDNA sequence of the flavoprotein subunit of human heart succinate dehydrogenase.