Scimp Antibodies

AND Scimp ELISA kits, Scimp Proteins

Many biological assays use antibodies to detect Scimp, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Scimp in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Scimp antibodies...

We validate the specificity of these antibodies to Scimp by testing them on tissues known to express Scimp positively and negatively. Browse below to find the Scimp antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Scimp Infographic by Boster Bio

All Scimp Products

Product

Figures

Specificity

Applications

Price

Anti-SCIMP Purified Monoclonal Antibody

Human

Flow Cytometry, IP, ICC, WB

$326
Cat # M12849
0.1 mg

C17orf87 (SCIMP) (NM_207103) Human Recombinant Protein

$1249
Cat # PROTQ6UWF3
20 µg

C17orf87 (SCIMP) (NM_207103) Human Over-expression Lysate

Human

$628
Cat # LS388325
100 µg

Scimp Overview

Facts about SLP adapter and CSK-interacting membrane protein.

SLP adapter and CSK-interacting membrane protein (Scimp)

Lipid tetraspanin-associated transmembrane adapter/mediator involved in major histocompatibility complex class II (MHC-II) signaling transduction. Required in creating the calcium response and improving ERK activity upon MHC-II stimulation (By similarity).

. .

Gene Information

Mouse
Gene Name:	Scimp
Uniprot:	Q3UU41
Entrez:	327957

Family

Belongs to:

No superfamily

Alternative Names

transmembrane protein C17orf87; C17orf87; chromosome 17 open reading frame 87; DTFT5783; FLJ32580; SLP adapter and CSK-interacting membrane protein; SLP adaptor and CSK interacting membrane protein; SLP65/SLP76, Csk-interacting membrane protein; UNQ5783

Molecular Weight

Mass (kDA):
17.14 kDA

Genomic Context


Mouse

Location:	11\|11 B3
Sequence:	11;

Tissue Specificity

Expressed in peripheral blood leukocytes (PBLs) (at protein level). Strongly expressed in the spleen and lymph nodes and weakly in other tissues of the immune system, including bone marrow, peripheral blood leukocytes (PBLs) and thymus. Not detected in the majority of nonimmune tissues, with the exception of lung. Expressed in antigen-presenting cells.

PTMs

Phosphorylation

Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Scimp

References

PMID: 21930792 by Draber P., et al. SCIMP, a transmembrane adapter protein involved in major histocompatibility complex class II signaling.

PMID: 27288407 by Kralova J., et al. The Transmembrane Adaptor Protein SCIMP Facilitates Sustained Dectin- 1 Signaling in Dendritic Cells.