Scavenger receptor class A member 5 (Scara5)

Ferritin receptor that mediates non-transferrin- dependent delivery of iron. Mediates cellular uptake of ferritin- bound iron by sparking ferritin endocytosis from the cell surface with consequent iron delivery within the cell.

Delivery of iron to cells by ferritin is required for the growth of specific cell types, suggesting the existence of cell type- specific mechanisms of iron traffic in organogenesis, which instead use transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney.