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Protein SCAI Antibodies

AND SCAI ELISA kits, Protein SCAI Proteins

Many biological assays use antibodies to detect Protein SCAI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein SCAI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein SCAI antibodies...

We validate the specificity of these antibodies to Protein SCAI by testing them on tissues known to express SCAI positively and negatively. Browse below to find the SCAI antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SCAI Infographic by Boster Bio

SCAI protein infographic

All SCAI Products

Product

Figures

Specificity

Applications

Price

SCAI (NM_173690) Human Recombinant Protein

$1249
Cat # PROTQ8N9R8
20 µg

SCAI (NM_173690) Human Over-expression Lysate

Human

$960
Cat # LS286205
100 µg

SCAI Overview

Facts about Protein SCAI.

SCAI 3D structure

SCAI 3D structure. Source: alphafold

Protein SCAI (SCAI)

Tumor suppressor which functions to suppress MRTFA- induced SRF transcriptional activity. May function in the RHOA- DIAPH1 signal transduction pathway and modulate cell migration via transcriptional regulation of ITGB1.

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Gene Information

Human
Gene Name:	SCAI
Uniprot:	Q8N9R8
Entrez:	286205

Gene Information

Family

Belongs to:

SCAI family

Family

Alternative Names

C9orf126; FLJ11758; FLJ36664; MGC120528; protein SCAI; suppressor of cancer cell invasion

Molecular Weight

Mass (kDA):
70.399 kDA

Molecular Weight

Genomic Context


Human

Location:	9q33.3
Sequence:	9; NC_000009.12 (124942608..125143528, complement)

Subcellular Localizations

Membrane; Single-pass membrane protein. Nucleus. Cytoplasm. Nuclear localization is required for inhibition of MRTFA.

Subcellular Localization

Diseases

Cardiovascular Diseases
Coronary Artery Disease
Heart Diseases
Coronary Heart Disease
Myocardial Infarction
Cerebrovascular Accident
Heart Failure
Carotid Artery Diseases
Atherosclerosis
Infarction
Aortic Valve Stenosis
Vascular Diseases
Acute Coronary Syndrome

Steroid Sulfatase Deficiency Disease
Heart Valve Disease
Malignant Neoplasms
Myocardial Ischemia
Hypertensive Disease
Peripheral Vascular Diseases
Ischemia

Disease

Pathways

Cell Migration
Pathogenesis
Acute Inflammatory Response
Cell Differentiation
Platelet Activation
Nuclear Export
Localization
Glomerular Filtration

Inflammatory Response
Carbon Fixation

Pathways

PTMs

Carboxylation

Nitration

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCAI

References

PMID: 19350017 by Brandt D.T., et al. SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin.