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- Table of Contents
Facts about Myotubularin-related protein 5.
The pocket is however sufficiently preserved to bind phosphorylated substrates, and perhaps shield them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts.
Human | |
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Gene Name: | SBF1 |
Uniprot: | O95248 |
Entrez: | 6305 |
Belongs to: |
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protein-tyrosine phosphatase family |
myotubularin-related protein 5; DENND7A; MTMR5; SET binding factor 1
Mass (kDA):
208.443 kDA
Human | |
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Location: | 22q13.33 |
Sequence: | 22; NC_000022.11 (50445000..50475035, complement) |
Cytoplasm. Cytoplasm, perinuclear region.
PMID: 9537414 by Cui X., et al. Association of SET domain and myotubularin-related proteins modulates growth control.
PMID: 9736772 by Laporte J., et al. Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.