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- Table of Contents
Facts about Stabilizer of axonemal microtubules 1.
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Human | |
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Gene Name: | SAXO1 |
Uniprot: | Q8IYX7 |
Entrez: | 158297 |
Belongs to: |
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FAM154 family |
Stabilizer of axonemal microtubules 1
Mass (kDA):
54.621 kDA
Human | |
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Location: | 9p22.1 |
Sequence: | 9; NC_000009.12 (18927650..19049506, complement) |
Widely expressed, with highest levels in testis. Expressed in mature spermatozoa (at protein level).
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, flagellum axoneme. In multi-ciliated cells, localizes to the basal bodies and in non-ciliated cells, to the centrosome. In spermatozoa, colocalizes with microtubules along the length of the axoneme from its proximal end to its distal tip and with tubulin at the distal end of the flagellum and at the proximal centriole.
PMID: 25673876 by Dacheux D., et al. Human FAM154A (SAXO1) is a microtubule-stabilizing protein specific to cilia and related structures.