SASH1 Antibodies

AND SASH1 ELISA kits, SASH1 Proteins

Many biological assays use antibodies to detect SASH1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SASH1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SASH1 antibodies...

We validate the specificity of these antibodies to SASH1 by testing them on tissues known to express SASH1 positively and negatively. Browse below to find the SASH1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SASH1 Infographic by Boster Bio

All SASH1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SASH1 Antibody

Human, Mouse

$405
Cat # A05644
100ul

SASH1 (NM_015278) Human Over-expression Lysate

Human

$960
Cat # LS023328
100 µg

SASH1 Overview

Facts about SAM and SH3 domain-containing protein 1.

SASH1 3D structure. Source: alphafold

SAM and SH3 domain-containing protein 1 (SASH1)

May have a role in a signaling pathway. Could act as a tumor suppressor.

Gene Information

Human
Gene Name:	SASH1
Uniprot:	O94885
Entrez:	23328

Family

Belongs to:

No superfamily

Alternative Names

dJ323M4; dJ323M4.1; KIAA0790RP3-323M4.1; PEPE1; Proline-glutamate repeat-containing protein; SAM and SH3 domain containing 1,2500002E12Rik; SAM and SH3 domain-containing protein 1; SH3D6A

Molecular Weight

Mass (kDA):
136.653 kDA

Genomic Context


Human

Location:	6q24.3-q25.1
Sequence:	6; NC_000006.12 (148193440..148552050)

Tissue Specificity

Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Malignant Tumor Of Colon
Malignant Neoplasm Of Breast
Colonic Neoplasms
Cell Invasion
Carcinoma
Mammary Neoplasms
Neoplasm Recurrence, Local
Adenoma
Melanoma

Metastatic Malignant Neoplasm To The Lung
Metastatic Malignant Neoplasm To The Liver
Glioma
Malignant Neoplasm Of Lung
Osteosarcoma
Carcinoma Breast Stage Iv

Pathways

Cell Cycle
Cell Proliferation
Methylation
Cell Adhesion
Cell Activation
Cell Migration
Cell-matrix Adhesion
Cell Growth
Intracellular Signal Transduction

Localization
Mast Cell Activation
Cell Cycle Arrest

PTMs

Phosphorylation

Methylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SASH1

References

PMID: 12771949 by Zeller C., et al. SASH1 - a candidate tumour suppressor gene on chromosome 6q24.3 is downregulated in breast cancer.

PMID: 23333244 by Zhou D., et al. SASH1 regulates melanocyte transepithelial migration through a novel Galphas-SASH1-IQGAP1-E-cadherin dependent pathway.