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- Table of Contents
Facts about Protein Smaug homolog 1.
Human | |
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Gene Name: | SAMD4A |
Uniprot: | Q9UPU9 |
Entrez: | 23034 |
Belongs to: |
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SMAUG family |
DKFZp434H0350; DKFZp686A1532; hSmaug1DKFZP434H0350; KIAA1053SMAUG1; protein Smaug homolog 1; SAM domain-containing protein 4A; SAMD4; Smaug 1; smaug homolog; Smaug; Smaug1; SMG; SMGA; sterile alpha motif domain containing 4; sterile alpha motif domain containing 4A; Sterile alpha motif domain-containing protein 4A
Mass (kDA):
79.415 kDA
Human | |
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Location: | 14q22.2 |
Sequence: | 14; NC_000014.9 (54567097..54793315) |
Cytoplasm. Cell projection, dendrite. Cell junction, synapse, synaptosome. Enriched in synaptoneurosomes (By similarity). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1.
PMID: 16221671 by Baez M.V., et al. Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules.