S1PR4 Antibodies

AND S1PR4 ELISA kits, S1PR4 Proteins

Many biological assays use antibodies to detect S1PR4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with S1PR4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop S1PR4 antibodies...

We validate the specificity of these antibodies to S1PR4 by testing them on tissues known to express S1PR4 positively and negatively. Browse below to find the S1PR4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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S1PR4 Infographic by Boster Bio

All S1PR4 Products

Product

Figures

Specificity

Applications

Price

Anti-EDG-6 S1PR4 Antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A09413-1
100ul

EDG6 (S1PR4) (NM_003775) Human Over-expression Lysate

Human

$628
Cat # LS008698
100 µg

S1PR4 Overview

Facts about Sphingosine 1-phosphate receptor 4.

S1PR4 3D structure. Source: alphafold

Sphingosine 1-phosphate receptor 4 (S1PR4)

Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most kinds of cells and tissues.

May be involved in cell migration processes which are specific for lymphocytes. .

Gene Information

Human
Gene Name:	S1PR4
Uniprot:	O95977
Entrez:	8698

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

EDG6; EDG6S1P receptor Edg-6; Endothelial differentiation G-protein coupled receptor 6; endothelial differentiation, G-protein-coupled receptor 6; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor6,endothelial differentiation, G protein coupled receptor 6; S1P receptor 4; S1P4; S1P4LPC1; S1PR4; SLP4; sphingosine 1-phosphate receptor 4; Sphingosine 1-phosphate receptor Edg-6; sphingosine-1-phosphate receptor 4

Molecular Weight

Mass (kDA):
41.623 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (3178769..3180332)

Tissue Specificity

Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Tumor Angiogenesis
Nervousness
Pertussis
Crest Syndrome

Pathways

Cell Migration
Angiogenesis

PTMs

Glycoprotein

Lipoprotein

Palmitate

Research Areas

Cell Biology
Cellular Markers
GPCR
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/S1PR4

References

PMID: 9790765 by Graeler M.H., et al. EDG6, a novel G protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue.

PMID: 10679247 by Yamazaki Y., et al. Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway.