RMND5B Antibodies

AND RMND5B ELISA kits, RMND5B Proteins

Many biological assays use antibodies to detect RMND5B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RMND5B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RMND5B antibodies...

We validate the specificity of these antibodies to RMND5B by testing them on tissues known to express RMND5B positively and negatively. Browse below to find the RMND5B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RMND5B Infographic by Boster Bio

All RMND5B Products

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Specificity

Applications

Price

RMND5B (NM_022762) Human Recombinant Protein

$813
Cat # PROTQ96G75
20 µg

RMND5B (NM_022762) Human Over-expression Lysate

Human

$628
Cat # LS064777
100 µg

RMND5B Overview

Facts about E3 ubiquitin-protein transferase RMND5B.

RMND5B 3D structure. Source: alphafold

E3 ubiquitin-protein transferase RMND5B (RMND5B)

Core part of the CTLH E3 ubiquitin-protein ligase complex that accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex (PubMed:29911972).

Catalytic activity of the complex is necessary for normal cell proliferation (PubMed:29911972). The CTLH E3 ubiquitin-protein ligase complex is not required for its degradation of enzymes involved in gluconeogenesis, such as FBP1 (PubMed:29911972).

Gene Information

Human
Gene Name:	RMND5B
Uniprot:	Q96G75
Entrez:	64777

Family

Belongs to:

No superfamily

Alternative Names

DKFZp434K0926; FLJ22318; protein RMD5 homolog B; required for meiotic nuclear division 5 homolog B (S. cerevisiae)

Molecular Weight

Mass (kDA):
44.414 kDA

Genomic Context


Human

Location:	5q35.3
Sequence:	5; NC_000005.10 (178130532..178150568)

Subcellular Localizations

Cytoplasm, cytosol.

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RMND5B

References

PMID: 25793641 by Pfirrmann T., et al. RMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development.

PMID: 29911972 by Lampert F., et al. The multi-subunit GID/CTLH E3 ligase promotes proliferation and targets the transcription factor Hbp1 for degradation.