REPS2 Antibodies

AND REPS2 ELISA kits, REPS2 Proteins

Many biological assays use antibodies to detect REPS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with REPS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop REPS2 antibodies...

We validate the specificity of these antibodies to REPS2 by testing them on tissues known to express REPS2 positively and negatively. Browse below to find the REPS2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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REPS2 Infographic by Boster Bio

All REPS2 Products

Product

Figures

Specificity

Applications

Price

Anti-REPS2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A09716
100ul

REPS2 (NM_004726) Human Recombinant Protein

$1249
Cat # PROTQ8NFH8
20 µg

REPS2 (NM_004726) Human Over-expression Lysate

Human

$960
Cat # LS009185
100 µg

REPS2 Overview

Facts about RalBP1-associated Eps domain-containing protein 2.

REPS2 3D structure. Source: alphafold

RalBP1-associated Eps domain-containing protein 2 (REPS2)

Involved in growth factor signaling through its influence on the Ral signaling pathway. .

Gene Information

Human
Gene Name:	REPS2
Uniprot:	Q8NFH8
Entrez:	9185

Family

Belongs to:

No superfamily

Alternative Names

partner of Ral-binding protein 1; POB1Partner of RalBP1; RALBP1 associated Eps domain containing 2; ralBP1-associated Eps domain-containing protein 2; RalBP1-interacting protein 2

Molecular Weight

Mass (kDA):
71.534 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (16946658..17220724)

Tissue Specificity

Expressed at high levels in the cerebrum, cerebellum, lung, kidney, and testis. Weakly expressed in the kidney. Relatively highly expressed in androgen-dependent as compared to androgen-independent prostate cancer cell lines and xenografts. Isoform 2 is down-regulated during progression of prostate cancer.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Neoplasms
Non-small Cell Lung Carcinoma
Cataract
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Lung
Sarcoma

Parkinson Disease
Neoplasms, Hormone-dependent
Tooth Abnormalities
Metastatic Prostate Cancer
Mammary Neoplasms

Interacting Proteins

BIN1
Eps15
GRB2
SFN
YWHAZ

Pathways

Endocytosis
Receptor-mediated Endocytosis
Transport
Regulation Of Endocytosis
Protein Glutathionylation
Reverse Transcription
Cell Proliferation
Cell Migration
Induction Of Apoptosis

Cell Death
Protein Deglutathionylation
Localization

PTMs

Phosphorylation
Glutathionylation

Deglutathionylation
Ribosylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/REPS2

References

PMID: 9422736 by Ikeda M., et al. Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral.

PMID: 12771942 by Oosterhoff J.K., et al. REPS2/POB1 is downregulated during human prostate cancer progression and inhibits growth factor signalling in prostate cancer cells.