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REG3A Antibodies
AND REG3A ELISA kits, REG3A Proteins
Many biological assays use antibodies to detect REG3A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with REG3A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop REG3A antibodies...
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REG3A Infographic by Boster Bio
All REG3A Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, WB
$250
Cat # PROTQ06141
2ug, 10ug, 1mg
Cat # PROTQ06141
2ug, 10ug, 1mg
Rat REG3A ELISA Kit PicoKine®
11 Q&As
Rat
ELISA
$499
Cat # EK1836
96 wells/kit, with removable strips.
Cat # EK1836
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK1834
96 wells/kit, with removable strips.
Cat # EK1834
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1835
96 wells/kit, with removable strips.
Cat # EK1835
96 wells/kit, with removable strips.
REG3A Overview
Facts about Regenerating islet-derived protein 3-alpha.
Regenerating islet-derived protein 3-alpha (REG3A)
Bactericidal C-type lectin which acts exclusively against Gram-positive germs and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
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Gene Information
| Human | |
|---|---|
| Gene Name: | REG3A |
| Uniprot: | Q06141 |
| Entrez: | 5068 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
hepatocarcinoma-intestine-pancreas; HIPpancreatitis-associated protein; Human proislet peptide; Lithostathine 3; pancreatic beta cell growth factor; Pancreatitis-associated protein 1; PAP homologous protein; PAP1FLJ18565; PAP2; PAPPAP-H; PBCGF; proliferation-inducing protein 34; proliferation-inducing protein 42; Reg III-alpha; REG3; Reg3A; REG-3-alpha; regenerating islet-derived 3 alpha; regenerating islet-derived protein 3-alpha; Regenerating islet-derived protein III-alpha; REG-III
Molecular Weight
Mass (kDA):
19.395 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p12 |
| Sequence: | 2; NC_000002.12 (79157006..79159753, complement) |
Tissue Specificity
Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level). Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.
Subcellular Localizations
Secreted. Found in the apical region of pancreatic acinar cells.
Diseases
- Carcinoma
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Liver Carcinoma
- Inflammation
- Diabetes Mellitus
- Liver Neoplasms
- Liver Cirrhosis
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Adenoma
- Skin Injury
Interacting Proteins
- MDFI
Pathways
- Cell Proliferation
- Secretion
- Cell Adhesion
- Regeneration
- Cell Migration
- Cell Division
- Chemotaxis
- Cell Cycle
- Insulin Secretion
- Dna Methylation
- Methylation
- Keratinocyte Proliferation
- Immune Response
PTMs
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/REG3A
bosterbio.com/bosterbio-gene-info-cards/REG3A
References
PMID: 7679928 by Itoh T., et al. Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP).
PMID: 1469087 by Orelle B., et al. Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases.