Rabenosyn-5 (RBSN)

Rab4/Rab5 effector protein behaving in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles.

Plays a role in the lysosomal trafficking of CTSD/cathepsin D in the Golgi to lysosomes. Also promotes the recycling of transferrin straight from early endosomes to the plasma membrane.