RNA-binding protein 8A Antibodies

AND RBM8A ELISA kits, RNA-binding protein 8A Proteins

Many biological assays use antibodies to detect RNA-binding protein 8A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNA-binding protein 8A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNA-binding protein 8A antibodies...

We validate the specificity of these antibodies to RNA-binding protein 8A by testing them on tissues known to express RBM8A positively and negatively. Browse below to find the RBM8A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RBM8A Infographic by Boster Bio

All RBM8A Products

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Specificity

Applications

Price

Y14 (RBM8A) (NM_005105) Human Recombinant Protein

$813
Cat # PROTQ9Y5S9
20 µg

Anti-Y14 (RBM8A) Mouse Monoclonal Antibody [Clone ID: OTI10B10]

Human, Mouse, Rat

$523
Cat # M02769
100 µl

Anti-Y14 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M02769-1
100 μl/vial

Y14 (RBM8A) (NM_005105) Human Over-expression Lysate

Human

$628
Cat # LS009939
100 µg

RBM8A Overview

Facts about RNA-binding protein 8A.

RBM8A 3D structure. Source: alphafold

RNA-binding protein 8A (RBM8A)

Core part of this splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure comprising core proteins and lots of peripheral nuclear and cytoplasmic related things that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.

The EJC marks the place of this exon-exon junction from the mature mRNA for the gene expression machinery and the core elements remain bound to spliced mRNAs throughout all phases of mRNA metabolism thereby influencing downstream processes such as nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The MAGOH-RBM8A heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP- bound EJC core onto spliced mRNA in a stable conformation.

Gene Information

Human
Gene Name:	RBM8A
Uniprot:	Q9Y5S9
Entrez:	9939

Family

Belongs to:

RBM8A family

Alternative Names

Binder of OVCA1-1; BOV-1; BOV-1A; BOV-1B; BOV-1C; MDS014; RBM8BRBM8; ribonucleoprotein RBM8; Ribonucleoprotein RBM8A; RNA binding motif protein 8A; RNA binding motif protein 8B; RNA-binding motif protein 8A; RNA-binding protein 8A; RNA-binding protein Y14; Y14; ZNRP; ZRNP1

Molecular Weight

Mass (kDA):
19.889 kDA

Genomic Context


Human

Location:	1q21.1
Sequence:	1; NC_000001.11 (145921556..145927484, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus. Nucleus speckle. Cytoplasm. Nucleocytoplasmic shuttling protein (PubMed:11030346). Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles (PubMed:19324961).