RACK1 Antibodies

AND RACK1 ELISA kits, RACK1 Proteins

Many biological assays use antibodies to detect RACK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RACK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RACK1 antibodies...

We validate the specificity of these antibodies to RACK1 by testing them on tissues known to express RACK1 positively and negatively. Browse below to find the RACK1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RACK1 Infographic by Boster Bio

All RACK1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GNB2L1 RACK1 Antibody

Human

IF, ICC, WB

$405
Cat # A02145
100ul

Anti-RACK1 Antibody

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$405
Cat # A02145-1
100ul

Human RACK1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP63244
Starting from 10ug

Anti-RACK1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02145-1
100 μl/vial

RACK1 (NM_006098) Human Over-expression Lysate

Human

$628
Cat # LS010399
100 µg

RACK1 Overview

Facts about Receptor of activated protein C kinase 1.

RACK1 3D structure. Source: alphafold

Receptor of activated protein C kinase 1 (RACK1)

Scaffolding protein involved in the recruitment, assembly and/or regulation of many different signaling molecules. Interacts with a huge selection of proteins and plays a role in many cellular processes.

Part of the 40S ribosomal subunit involved in translational repression (PubMed:23636399). Involved from the initiation of the ribosome quality control (RQC), a pathway that happens when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (PubMed:28132843).

Gene Information

Human
Gene Name:	RACK1
Uniprot:	P63244
Entrez:	10399

Family

Belongs to:

WD repeat G protein beta family

Alternative Names

Receptor of activated protein C kinase 1

Molecular Weight

Mass (kDA):
35.077 kDA

Genomic Context


Human

Location:	5q35.3
Sequence:	5; NC_000005.10 (181236897..181243906, complement)

Tissue Specificity

In the liver, expressed at higher levels in activated hepatic stellate cells than in hepatocytes or Kupffer cells. Up-regulated in hepatocellular carcinomas and in the adjacent non-tumor liver tissue.

Subcellular Localizations

Cell membrane; Peripheral membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Perikaryon. Cell projection, dendrite. Cell projection, phagocytic cup. Recruited to the plasma membrane through interaction with KRT1 which binds to membrane-bound ITGB1 (PubMed:17956333). Also associated with the membrane in oncogene-transformed cells (PubMed:11884618). PKC activation induces translocation from the perinuclear region to the cell periphery (PubMed:11279199). In the brain, detected mainly in cell bodies and dendrites with little expression in axonal fibers or nuclei (By similarity).

Interacting Proteins

ACHE
ACTN2
AGO2
BCL2L11
DYNLL1

EED
IFNAR2
INCA1
LARP4B
LRP12

LYN
PAG1
PARK7
PIAS2
PPID

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RACK1

References

PMID: 2499885 by Guillemot F., et al. Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex.

PMID: 9584165 by Chang B.Y., et al. RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells.