RABGGTA Antibodies

AND RABGGTA ELISA kits, RABGGTA Proteins

Many biological assays use antibodies to detect RABGGTA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RABGGTA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RABGGTA antibodies...

We validate the specificity of these antibodies to RABGGTA by testing them on tissues known to express RABGGTA positively and negatively. Browse below to find the RABGGTA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RABGGTA Infographic by Boster Bio

All RABGGTA Products

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Product

Figures

Specificity

Applications

Price

RABGGTA (NM_004581) Human Recombinant Protein

$1062
Cat # PROTQ92696
20 µg

RABGGTA (NM_182836) Human Over-expression Lysate

Human

$628
Cat # LS005875
100 µg

RABGGTA Overview

Facts about Geranylgeranyl transferase type-2 subunit alpha.

RABGGTA 3D structure. Source: alphafold

Geranylgeranyl transferase type-2 subunit alpha (RABGGTA)

Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. .

Gene Information

Human
Gene Name:	RABGGTA
Uniprot:	Q92696
Entrez:	5875

Family

Belongs to:

protein prenyltransferase subunit alpha family

Alternative Names

EC 2.5.1.60; Geranylgeranyl transferase type II subunit alpha; geranylgeranyl transferase type-2 subunit alpha; protein prenyltransferase alpha subunit repeat containing 3; PTAR3; Rab geranylgeranyltransferase subunit alpha; Rab geranyl-geranyltransferase subunit alpha; Rab geranylgeranyltransferase, alpha subunit; Rab GG transferase alpha; Rab GGTase alpha

Molecular Weight

Mass (kDA):
65.072 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (24265538..24271627, complement)

Diseases

Hereditary Diseases
Gray Platelet Syndrome
Hemorrhage
Blood Coagulation Disorders
Hermanski-pudlak Syndrome
Thrombocytosis
Platelet Storage Pool Deficiency

Albinism

Interacting Proteins

CHM
RABGGTB

Pathways

Prenylation
Hemostasis
Localization

PTMs

Geranylgeranylation

Prenylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RABGGTA

References

PMID: 8954794 by van Bokhoven H., et al. cDNA cloning and chromosomal localization of the genes encoding the alpha- and beta-subunits of human Rab geranylgeranyl transferase: the 3' end of the alpha-subunit gene overlaps with the transglutaminase 1 gene promoter.

PMID: 9196026 by Song H.-J., et al. The genes encoding geranylgeranyl transferase alpha-subunit and transglutaminase 1 are very closely linked but not functionally related in terminally differentiating keratinocytes.