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- Table of Contents
Facts about Ras-related protein Rab-32.
Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.
Human | |
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Gene Name: | RAB32 |
Uniprot: | Q13637 |
Entrez: | 10981 |
Belongs to: |
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small GTPase superfamily |
RAB32, member RAS oncogene family; ras-related protein Rab-32
Mass (kDA):
24.997 kDA
Human | |
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Location: | 6q24.3 |
Sequence: | 6; NC_000006.12 (146543833..146554953) |
Widely expressed with high levels in heart, liver, kidney, bone marrow, testis, colon and fetal lung.
Mitochondrion. Mitochondrion outer membrane; Lipid-anchor. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Melanosome membrane. Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991).
PMID: 11784320 by Bao X., et al. Molecular cloning, bacterial expression and properties of Rab31 and Rab32.
PMID: 12186851 by Alto N.M., et al. Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics.