Relaxin-3 receptor 1 Antibodies

AND RXFP3 ELISA kits, Relaxin-3 receptor 1 Proteins

Many biological assays use antibodies to detect Relaxin-3 receptor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Relaxin-3 receptor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Relaxin-3 receptor 1 antibodies...

We validate the specificity of these antibodies to Relaxin-3 receptor 1 by testing them on tissues known to express RXFP3 positively and negatively. Browse below to find the RXFP3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RXFP3 Infographic by Boster Bio

All RXFP3 Products

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Anti-RXFP3/Salpr Antibody

3 Q&As

Human, Mouse, Rat

ELISA, WB

$335
Cat # A06438
100ul

Relaxin 3 receptor 1 (RXFP3) (NM_016568) Human Over-expression Lysate

Human

$960
Cat # LS051289
100 µg

RXFP3 Overview

Facts about Relaxin-3 receptor 1.

RXFP3 3D structure. Source: alphafold

Relaxin-3 receptor 1 (RXFP3)

Receptor for RNL3/relaxin-3.
Binding of the ligand inhibit cAMP accumulation.

Gene Information

Human
Gene Name:	RXFP3
Uniprot:	Q9NSD7
Entrez:	51289

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor SALPR; GPCR135; GPCR135MGC141998; G-protein coupled receptor SALPR; relaxin 3 receptor 1; Relaxin family peptide receptor 3RLN3 receptor 1; relaxin/insulin-like family peptide receptor 3; relaxin-3 receptor 1; RLN3R1; RLN3R1MGC142000; RXFP3; RXFPR3; SALPRG-protein coupled receptor GPCR135; Somatostatin- and angiotensin-like peptide receptor; somatostatin and angiotensin-like peptide receptor

Molecular Weight

Mass (kDA):
51.124 kDA

Genomic Context


Human

Location:	5p13.2
Sequence:	5; NC_000005.10 (33936386..33938918)

Tissue Specificity

Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Chimera Disorder
Fibrosis
Obesity
Nervousness
Scleroderma
Infertility
Cardiovascular Diseases
Pituitary Diseases
Asthma
Pertussis
Anxiety Disorders
Heart Failure
Physiological Stress

Cryptorchidism
Depressive Disorder
Disease Of Adrenal Medulla
Dyslipidemias
Eating Disorders
Infarction
Endometrial Neoplasms

Pathways

Localization
Circadian Rhythm
Energy Homeostasis
Receptor Internalization
Cognition
Regulation Of Energy Homeostasis
Response To Stress
Gene Silencing
Methylation
Regeneration

Embryo Implantation
Tissue Remodeling
Regulation Of Appetite
Feeding Behavior
Wound Healing

PTMs

Phosphorylation
Cleavage

Amidation
Methylation

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RXFP3

References

PMID: 10806363 by Matsumoto M., et al. The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors.

PMID: 14522968 by Liu C., et al. Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein coupled receptor GPCR135.