Relaxin receptor 2 Antibodies

AND RXFP2 ELISA kits, Relaxin receptor 2 Proteins

Many biological assays use antibodies to detect Relaxin receptor 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Relaxin receptor 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Relaxin receptor 2 antibodies...

We validate the specificity of these antibodies to Relaxin receptor 2 by testing them on tissues known to express RXFP2 positively and negatively. Browse below to find the RXFP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RXFP2 Infographic by Boster Bio

All RXFP2 Products

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Price

Anti-Relaxin Receptor 2 RXFP2 Antibody

Human, Mouse, Rat

$399
Cat # A04848
100μl

Anti-GPCR LGR8/RXFP2 Antibody Picoband®

13 Q&As

Human

Flow Cytometry, WB

$370
Cat # A04848-1
100 μg/vial

LGR8 (RXFP2) (NM_130806) Human Over-expression Lysate

Human

$960
Cat # LS122042
100 µg

RXFP2 Overview

Facts about Relaxin receptor 2.

RXFP2 3D structure. Source: alphafold

Relaxin receptor 2 (RXFP2)

Receptor for relaxin.
The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP.

May also be a receptor for Leydig insulin-like peptide (INSL3). .

Gene Information

Human
Gene Name:	RXFP2
Uniprot:	Q8WXD0
Entrez:	122042

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein coupled receptor affecting testicular descent; Gpr106; GPR106G-protein coupled receptor 106; Great; GREATRelaxin family peptide receptor 2; INSL3R; leucine-rich repeat-containing G protein-coupled receptor 8; Leucine-rich repeat-containing G-protein coupled receptor 8; Lgr8; LGR8.1; LGR8G-protein coupled receptor affecting testicular descent; Relaxin R2; relaxin receptor 2; relaxin/insulin-like family peptide receptor 2; RelaxinR2; RLN2R; Rxfp2; RXFPR2

Molecular Weight

Mass (kDA):
86.453 kDA

Genomic Context


Human

Location:	13q13.1
Sequence:	13; NC_000013.11 (31739526..31803389)

Tissue Specificity

Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Cryptorchidism
Congenital Abnormality
Infertility
Malignant Neoplasms
Neoplasms
Undescended Testes - Bilateral
Tumor Angiogenesis
Heart Failure
Endometrial Polyp
Pertussis
Neoplasm Metastasis
Carcinoma
Fibrosis

Osteoporosis
Cardiac Failure Acute
Scleroderma
Carcinogenesis
Malignant Neoplasm Of Testis
Neoplasm Invasiveness
Unilateral Undescended Testis

Pathways

Cell Proliferation
Spermatogenesis
Localization
Secretion
Oocyte Maturation
Angiogenesis
Embryo Development
Sex Determination
Cell Differentiation
Parturition
Glycosylation
Aging
Wound Healing

Vasodilation
Male Sex Determination
Osteoblast Proliferation
Developmental Maturation
Vasculogenesis
Cell Maturation
Autocrine Signaling

PTMs

Phosphorylation

Cleavage

Glycosylation

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RXFP2

References

PMID: 11809971 by Hsu S.Y., et al. Activation of orphan receptors by the hormone relaxin.

PMID: 12217959 by Gorlov I.P., et al. Mutations of the GREAT gene cause cryptorchidism.