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- Table of Contents
Facts about Reticulon-4-interacting protein 1, mitochondrial.
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Human | |
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Gene Name: | RTN4IP1 |
Uniprot: | Q8WWV3 |
Entrez: | 84816 |
Belongs to: |
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zinc-containing alcohol dehydrogenase family |
MGC12934; NIMPNOGO-interacting mitochondrial protein; reticulon 4 interacting protein 1; reticulon-4-interacting protein 1, mitochondrial
Mass (kDA):
43.59 kDA
Human | |
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Location: | 6q21 |
Sequence: | 6; NC_000006.12 (106559237..106630921, complement) |
Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.
Mitochondrion outer membrane. Colocalizes with the endoplasmic reticulum HSPA5 at spots corresponding to contacts with mitochondria.
PMID: 12067236 by Hu W.-H., et al. Identification and characterization of a novel Nogo-interacting mitochondrial protein (NIMP).
PMID: 26593267 by Angebault C., et al. Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies.