Reticulon-4 Antibodies

AND RTN4 ELISA kits, Reticulon-4 Proteins

Many biological assays use antibodies to detect Reticulon-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Reticulon-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Reticulon-4 antibodies...

We validate the specificity of these antibodies to Reticulon-4 by testing them on tissues known to express RTN4 positively and negatively. Browse below to find the RTN4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: ADCK1

RTN4 Infographic by Boster Bio

All RTN4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Nogo Monoclonal Antibody

1 Q&As

Human

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M01844
100 μl

Anti-NogoA RTN4 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, ICC, WB

$449
Cat # A01844
0.1 mg

Anti-Nogo B RTN4 Antibody

Human, Mouse

Flow Cytometry, IP, IF, IHC, ICC, WB

$405
Cat # A01844-1
100ul

Anti-Nogo A/RTN4 Antibody Picoband®

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01844-2
100 μg/vial

Nogo A (RTN4) (NM_020532) Human Over-expression Lysate

Human

$960
Cat # LS057142
100 µg

RTN4 Overview

Facts about Reticulon-4.

RTN4 3D structure. Source: alphafold

Reticulon-4 (RTN4)

Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and expansion in the developing nervous system.

Involved in down-regulation of development, insertion of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons through an RTN4R-LINGO1 containing receptor complex (By similarity).

Gene Information

Human
Gene Name:	RTN4
Uniprot:	Q9NQC3
Entrez:	57142

Family

Belongs to:

No superfamily

Alternative Names

ASY; foocen; Human NogoA; KIAA0886; My043 protein; Nbla00271; Nbla10545; neurite growth inhibitor 220; Neurite outgrowth inhibitor; Neuroendocrine-specific protein C homolog; Neuroendocrine-specific protein; NI220/250; Nogo protein; NOGO-A; Nogo-B; NOGOC; Nogo-C; NOGORTN4-B1; NSP; NSP-CL; reticulon 4; reticulon 5; reticulon-4; reticulon-5; RTN4-A; RTN4-B2; RTN4-C; RTN-x

Molecular Weight

Mass (kDA):
129.931 kDA

Genomic Context


Human

Location:	2p16.1
Sequence:	2; NC_000002.12 (54972189..55137831, complement)

Tissue Specificity

Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle. Isoform 2 is widely expressed except for the liver. Isoform 3 is expressed in brain, skeletal muscle and adipocytes. Isoform 4 is testis- specific.

Subcellular Localizations

[Isoform A]: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein; Cytoplasmic side. Anchored to the membrane of the endoplasmic reticulum (ER) through 2 putative transmembrane domains. Localizes throughout the ER tubular network (PubMed:27619977). Co-localizes with TMEM33 at the ER sheets.; [Isoform B]: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein; Extracellular side. Cell junction. Mainly located on endoplasmic reticulum tubules and sheet edges (PubMed:27786289). Upon ICAM1 engagemen