Reticulon-1 Antibodies

AND RTN1 ELISA kits, Reticulon-1 Proteins

Many biological assays use antibodies to detect Reticulon-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Reticulon-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Reticulon-1 antibodies...

We validate the specificity of these antibodies to Reticulon-1 by testing them on tissues known to express RTN1 positively and negatively. Browse below to find the RTN1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RTN1 Infographic by Boster Bio

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Reticulon 1 (RTN1) (NM_021136) Human Over-expression Lysate

Human

$628
Cat # LS006252
100 µg

RTN1 Overview

Facts about Reticulon-1.

RTN1 3D structure. Source: alphafold

Reticulon-1 (RTN1)

May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. .

Gene Information

Human
Gene Name:	RTN1
Uniprot:	Q16799
Entrez:	6252

Family

Belongs to:

No superfamily

Alternative Names

NSP-A; RTN1; RTN1A; RTN1-A

Molecular Weight

Mass (kDA):
83.618 kDA

Genomic Context


Human

Location:	14q23.1
Sequence:	14; NC_000014.9 (59595976..59871288, complement)

Tissue Specificity

Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Lung
Carcinoma
Neoplasms
Small Cell Carcinoma Of Lung
Nervousness
Lung Neoplasms
Neuroblastoma
Non-small Cell Lung Carcinoma
Neurodegenerative Disorders
Tissue Adhesions
Adenocarcinoma

Carcinoid Tumor
Malignant Squamous Cell Neoplasm
Convulsions
Alzheimer's Disease
Neuroendocrine Tumors
Pheochromocytoma
Malignant Paraganglionic Neoplasm

Interacting Proteins

MANF
SDCBP

Pathways

Localization
Regeneration
Transport
Cell Death
Secretion
Cell Adhesion
Brain Development
Pathogenesis
Regulation Of Gene Expression
Hormone Secretion
Nucleocytoplasmic Transport
Rna Interference
Regulation Of Signaling

Proteolysis
Axon Regeneration
Immune Response
Negative Regulation Of Signaling
Chromosome Segregation
Myelination
Cerebellum Development

PTMs

Acetylation
Phosphorylation

Deacetylation
Cleavage

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RTN1

References

PMID: 7685762 by Roebroek A.J.M., et al. Cloning and expression of alternative transcripts of a novel neuroendocrine-specific gene and identification of its 135-kDa translational product.

PMID: 8833145 by Roebroek A.J.M., et al. Genomic organization of the human NSP gene, prototype of a novel gene family encoding reticulons.