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- Table of Contents
Facts about Remodeling and spacing factor 1.
In case of infection by HBV, together with pX, it represses TNF-alpha triggered NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain (PubMed:11944984, PubMed:11788598).
Human | |
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Gene Name: | RSF1 |
Uniprot: | Q96T23 |
Entrez: | 51773 |
Belongs to: |
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No superfamily |
HBV pX associated protein-8; HBXAPp325 subunit of RSF chromatin-remodeling complex; hepatitis B virus x associated protein; Hepatitis B virus X-associated protein; p325; remodeling and spacing factor 1; RSF-1; XAP8HBV pX-associated protein 8
Mass (kDA):
163.821 kDA
Human | |
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Location: | 11q14.1 |
Sequence: | 11; NC_000011.10 (77660009..77872232, complement) |
Ubiquitously expressed.
Nucleus.
PMID: 11944984 by Shamay M., et al. HBXAP, a novel PHD-finger protein, possesses transcription repression activity.
PMID: 11788598 by Shamay M., et al. Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription.