Retinoschisin Antibodies

AND RS1 ELISA kits, Retinoschisin Proteins

Many biological assays use antibodies to detect Retinoschisin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Retinoschisin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Retinoschisin antibodies...

We validate the specificity of these antibodies to Retinoschisin by testing them on tissues known to express RS1 positively and negatively. Browse below to find the RS1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RS1 Infographic by Boster Bio

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Anti-RS1 Antibody Picoband®

Human, Mouse

ELISA, WB

$370
Cat # A01128
100 μg/vial

RS1 Overview

Facts about Retinoschisin.

RS1 3D structure. Source: alphafold

Retinoschisin (RS1)

Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides (By similarity). May play a role in cell-cell adhesion processes in the retina, through homomeric interaction between octamers present on the surface of two neighboring cells (PubMed:27114531).

Required for normal structure and function of the retina (PubMed:19093009). .

Gene Information

Human
Gene Name:	RS1
Uniprot:	O15537
Entrez:	6247

Family

Belongs to:

No superfamily

Alternative Names

retinoschisin 1; retinoschisis (X-linked, juvenile) 1; RS; XL; X-linked juvenile retinoschisis protein; XLRS1retinoschisin

Molecular Weight

Mass (kDA):
25.592 kDA

Genomic Context


Human

Location:	Xp22.13
Sequence:	X; NC_000023.11 (18639688..18672108, complement)

Tissue Specificity

Restricted to the retina (at protein level) (PubMed:10915776). Detected in the inner segment of the photoreceptors, the inner nuclear layer, the inner plexiform layer and the ganglion cell layer (at protein level). At the macula, expressed in both the outer and inner nuclear layers and in the inner plexiform layer (at protein level) (PubMed:10915776). Detected in retina (PubMed:9326935). Detected only within the photoreceptor cell layer, most prominently within the inner segments of the photoreceptors (PubMed:10915776). Undetectable in the inner plexiform layers and the inner nuclear layer (PubMed:10915776).

Subcellular Localizations

Secreted. Cell membrane; Peripheral membrane protein; Extracellular side. Binds to phosphatidylserine-containing lipid membranes and embeds itself partially into the lipid bilayer. Lipid-binding requires the presence of Ca(2+) ions.