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- Table of Contents
Facts about Ras-responsive element-binding protein 1.
Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR.
Human | |
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Gene Name: | RREB1 |
Uniprot: | Q92766 |
Entrez: | 6239 |
Belongs to: |
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krueppel C2H2-type zinc-finger protein family |
DNA-binding protein; FINB; Finger protein in nuclear bodies; hindsight homolog; HNT; LZ321; Raf-responsive zinc finger protein LZ321; ras responsive element binding protein 1; ras-responsive element-binding protein 1; RREB-1; Zep-1; zinc finger motif enhancer binding protein 1; Zinc finger motif enhancer-binding protein 1; zinc finger motif-enhancer binding-protein 1
Mass (kDA):
181.42 kDA
Human | |
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Location: | 6p24.3 |
Sequence: | 6; NC_000006.12 (7107743..7251980) |
Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
Nucleus speckle.
PMID: 9305772 by Fujimoto-Nishiyama A., et al. A novel zinc finger protein, Finb, is a transcriptional activator and localized in nuclear bodies.
PMID: 15067362 by Date S., et al. Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene.