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Rragd Antibodies
AND Rragd ELISA kits, Rragd Proteins
Many biological assays use antibodies to detect Rragd, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rragd in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rragd antibodies...
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Rragd Overview
Facts about Ras-related GTP-binding protein D.
Ras-related GTP-binding protein D (Rragd)
Guanine nucleotide-binding protein forming heterodimeric Rag complexes needed for the amino acid-induced relocalization of mTORC1 into the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids (By similarity).
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Gene Information
| Mouse | |
|---|---|
| Gene Name: | Rragd |
| Uniprot: | Q7TT45 |
| Entrez: | 52187 |
Family
| Belongs to: |
|---|
| GTR/RAG GTP-binding protein family |
Alternative Names
bA11D8.2.1; DKFZP761H171; FLJ44176; Rag D protein; Rag D; RAGD; Ras-related GTP binding D; ras-related GTP-binding protein D
Molecular Weight
Mass (kDA):
51.232 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 4 A5|4 14.57 cM |
| Sequence: | 4; |
Diseases
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Melanocytic Nevus
- Skin Neoplasms
- Malignant Neoplasms
- Obesity
- Neoplasms
- Melanoma
Pathways
- Cell Growth
- Localization
- Rna Interference
PTMs
- Phosphorylation
Research Areas
- Cancer
- mTOR Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Rragd
bosterbio.com/bosterbio-gene-info-cards/Rragd
References
PMID: 25259925 by Peng M., et al. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.