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- Table of Contents
Facts about 40S ribosomal protein SA.
Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.
Human | |
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Gene Name: | RPSA |
Uniprot: | P08865 |
Entrez: | 3921 |
Belongs to: |
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universal ribosomal protein uS2 family |
37 kDa laminin receptor precursor; 37/67 kDa laminin receptor; 37LRPNEM/1CHD4; 67 kDa laminin receptor; 67kD, ribosomal protein SA; 67LR; Colon carcinoma laminin-binding protein; LAMBR37 kDa laminin receptor; laminin binding protein; laminin receptor 1 (67kD, ribosomal protein SA); Laminin receptor 1; Laminin-binding protein precursor p40; LAMR 1 ; lamR; LAMR140S ribosomal protein SA; LBP; LBP/p40; LRP; LRP/LR; Multidrug resistance-associated protein MGr1-Ag; p40; ribosomal protein SA
Mass (kDA):
32.854 kDA
Human | |
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Location: | 3p22.1 |
Sequence: | 3; NC_000003.12 (39406720..39412542) |
Cell membrane. Cytoplasm. Nucleus. 67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus (By similarity). Colocalizes with PPP1R16B in the cell membrane.
PMID: 2970639 by Yow H., et al. Increased mRNA expression of a laminin-binding protein in human colon carcinoma: complete sequence of a full-length cDNA encoding the protein.
PMID: 2543954 by van den Ouweland A.M.W., et al. Characteristics of a multicopy gene family predominantly consisting of processed pseudogenes.
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